Since October 7, 2015, the game has used a 5/69 (white balls) + 1/26 (Powerballs) matrix from which winning numbers are chosen, resulting in odds of 1 in 292,201,338 of winning a jackpot per play. Eastern Time, at the Florida Lottery's headquarters in Tallahassee. Monday drawings were added to help boost sales and increase jackpot amounts. From 1992 to 2021, Powerball drawings were held biweekly on Wednesdays and Saturdays. It is overseen by the Multi-State Lottery Association (MUSL), which also manages other large jackpot games such as the Mega Millions. Powerball is an American lottery game offered by 45 states, the District of Columbia, Puerto Rico and the U.S.